在光信号传导并调节哺乳动物外周器官的基因表达和能量代谢的分子生物学研究方面,做出了一些开创性的工作。这项工作的重要性不仅有重要的基础科学意义,而且有潜在的应用价值。这种信号的分子传导过程联系着能量的代谢过程,与许多重要的疾病如II型糖尿病,肥胖症以及癌症的发生机理有密切联系,其中的体温控制技术在外科手术治疗上有很大的应用前景。这些研究成果部分已发表在2006年1月《Nature》上,其他的工作也将发表在一些高影响因子的杂志上。国际同行迅速对这项工作做出了积极的评述。Cell出版社的《Current Biology》在2006年4月专门对此工作发表评述文章。 Selected Publications 1. Jianfa Zhang, Krista Kaasik, Michael R. Blackbum & Cheng Chi Le. Constant darkness is a circadian metabolic signal in mammals. Nature. 2006, 439(7074):340-3. 2.Jianfa Zhang, Xia Ding, Liuyan Yang & Zhiming Kong. A serum-free medium for colony growth and hyaluronic acid production by Streptococcus zooepidemicus NJUST01. Appl Microbiol Biotechnol. 2006 72:168-172 3.Xi Ding, Jianfa Zhang*, Xianghong Xu, Zhili Liu. Structural Features and Hypoglycemic Activity of an Exopolysaccharide Produced by Sorangium cellulosum. Letters In Applied Microbiology, 2004; 38(3):223-8. 4.Jianfa Zhang, Ruiyong Wang, Pengjiu Jiang, Zhili Liu. Production of an exopolysaccharide bioflocculant by Sorangium cellulosum. Letters in Applied Microbiology, 2002,34(3):178-181 5.Jianfa Zhang, Zhili Liu. Characterization of a biolocculant produced by the Marine Myxobacterium Nannocystic sp.NU-2 Applied Microbiology and Biotechnology, 2002, 59:517-522 6.Jianfa Zhang, Xianghong Xu, Houming Wu and zhili Liu. Structural Characterization of an exopolysaccharide from the Myxobacterium Sorangium Cellulosum NUST06. Chinese chemical le... 在光信号传导并调节哺乳动物外周器官的基因表达和能量代谢的分子生物学研究方面,做出了一些开创性的工作。这项工作的重要性不仅有重要的基础科学意义,而且有潜在的应用价值。这种信号的分子传导过程联系着能量的代谢过程,与许多重要的疾病如II型糖尿病,肥胖症以及癌症的发生机理有密切联系,其中的体温控制技术在外科手术治疗上有很大的应用前景。这些研究成果部分已发表在2006年1月《Nature》上,其他的工作也将发表在一些高影响因子的杂志上。国际同行迅速对这项工作做出了积极的评述。Cell出版社的《Current Biology》在2006年4月专门对此工作发表评述文章。 Selected Publications 1. Jianfa Zhang, Krista Kaasik, Michael R. Blackbum & Cheng Chi Le. Constant darkness is a circadian metabolic signal in mammals. Nature. 2006, 439(7074):340-3. 2.Jianfa Zhang, Xia Ding, Liuyan Yang & Zhiming Kong. A serum-free medium for colony growth and hyaluronic acid production by Streptococcus zooepidemicus NJUST01. Appl Microbiol Biotechnol. 2006 72:168-172 3.Xi Ding, Jianfa Zhang*, Xianghong Xu, Zhili Liu. Structural Features and Hypoglycemic Activity of an Exopolysaccharide Produced by Sorangium cellulosum. Letters In Applied Microbiology, 2004; 38(3):223-8. 4.Jianfa Zhang, Ruiyong Wang, Pengjiu Jiang, Zhili Liu. Production of an exopolysaccharide bioflocculant by Sorangium cellulosum. Letters in Applied Microbiology, 2002,34(3):178-181 5.Jianfa Zhang, Zhili Liu. Characterization of a biolocculant produced by the Marine Myxobacterium Nannocystic sp.NU-2 Applied Microbiology and Biotechnology, 2002, 59:517-522 6.Jianfa Zhang, Xianghong Xu, Houming Wu and zhili Liu. Structural Characterization of an exopolysaccharide from the Myxobacterium Sorangium Cellulosum NUST06. Chinese chemical letters,2003, 14(1):51-53 |