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华中农业大学水产学院导师介绍:林蠡

 林 蠡 【教授】姓名 林 蠡 性别 男职称 教授 学位 博士 电话 027-87282113 邮箱 linli@mail.hzau.edu.cn 工作单位 华中农业大学水产学院水生动物医学系 研究方向 水生动物疾病学;水生动物免
 

林 蠡 【教授】

姓名 林 蠡 性别 照片
职称 教授 学位 博士
电话 027-87282113 邮箱 linli@mail.hzau.edu.cn
工作单位 华中农业大学水产学院水生动物医学系
研究方向 水生动物疾病学;水生动物免疫学;水环境调控;耐药性;免疫增强剂、疫苗与药物研发
教育经历 1998.09-2004.12,中山大学,动物学,博 士
2002.09-2004.09,汉堡大学(德国),动物学,博士生
2001.09-2002.08,同济大学,德语,学习
1991.09-1994.07,华南师范大学,动物学,硕士
1987.09-1991.07,中国海洋大学,水产养殖,学士
主要职历 2012.12-至今,华中农业大学,湖北省“楚天学者” 特聘教授,博士生导师
2009.11-2012.11,U. of Saskatchewan (加拿大),博士后
2008.02-2009. 10,Rice University(美国),博士后
2005.07-2008.01,Pennsylvania State University(美国),博士后
2000.07-2000. 12,日本国立渔业研究所,鱼病研修
2004.10 -2005.06,广东省海洋与渔业局技术推广部,副部长,增殖科科长
1998.08-2004.09,广东省大亚湾水产试验中心,海水养殖,病害部主任
1994.07-1998.07,广东省西江水产资源增殖中心,淡水养殖,场长
科研成果 发表文章60多篇,其中SCI文章40多篇;国际专利2项,国内专利1项;参编专著2部。主要代表作如下( 带*号为通信作者,带+号为共同第一作者):
  1. Yachan Ji+, Jinquan Li+, Zhendong Qin, Aihua Li, Zemao Gu, Xiaoling Liu, Li Lin, Yang Zhou*. Contribution of nuclease to the pathogenesis of Aeromonas hydrophila.Virulence, 2015, accepted. SCI IF:3.319.
  2. Feifei Zheng, Muhammad Asim, Jiangfeng Lan, Lijuan Zhao, Shun Wei, Nan Chen, Xiaolin Liu, Yang Zhou*, Li Lin*.Danio rerio) during Infection with Aeromonas Sobria.Molecular Cloning and Functional Characterization of Mannose Receptor in Zebra Fish (International Journal of Molecular Sciences, 2015,16:10997-10112. SCI IF : 2.3
  3. Xianqin Hu, Xiaozhe Fu, Ningqiu Li*, Xingxing Dong,Lijuan Zhao,Jiangfeng Lan,WeiJi,Weidong Zhou, Taoshan Ai, Shuqin Wu, Li Lin*. Transcriptomic analysis of Mandarin fish brain cells infected with infectious spleen and kidney necrosis virus with an emphasis on retinoic acid-inducible gene 1-like receptors and apoptosis pathways. Fish and Shellfish Immunology, 2015, 45:619-629. SCI IF:3.0. JCR 一区)
  4. Dong X, Qin Z, Hu X, Lan J, Yuan G, Asim M, Zhou Y, Ai T, Mei J*, Lin L*. Molecular cloning and functional characterization of cyclophilin A in yellow catfish (Pelteobagrus fulvidraco). Fish and Shellfish Immunology, 2015,45:422-430. SCI IF:3.0. JCR一区)
  5. Li L, Luo Y, Gao Z, Huang J, Zheng X, Nie H, Zhang J, Lin L, Yuan J. Molecular characterisation and prevalence of a new genotype of Cyprinid herpesvirus 2 in mainland China. Can J Microbiol. 2015, 13:1-7. SCI IF:1.2.
  6. Wenjun Xu, Zhendong Qin, Hui Shi, Nan Jiang, Yang Zhou, Xiaoling Liu, Jianjun Xie,Genshen Wang, Weimin Wang, Muhammad Asim, Lingbing Zeng, Li Lin*. Mass mortality associated with a viral-induced anaemia in cage-reared large yellow croaker, Larimichthys crocea (Richardson). Journal of Fish Diseases, 2015;38(5):499-502. SCI IF: 1.5. JCR 二区)
  7. Xiaodan Liu, Jiannan Huang, Shaoping Weng, Xianqin Hu, Wenjie Chen, Zhendong Qin, Xingxing Dong, Xiaoling Liu, Yang Zhou, Muhammad Asim, Weimin Wang, Jianguo He*, Li Lin*. Infections of nervous necrosis virus in wild and cage-reared marine fish from South China Sea with unexpected wide host ranges. Journal of Fish Diseases, 2015;38(6):533-40.SCI IF: 1.5. JCR 二区)
  8. Wenwen Wang, Muhammad Asim, Lizhu Yi, Abeer M Hegazy, Xianqin Hu, Yang Zhou, Taoshan Ai, Li Lin*. Abortive infection of snakehead fish vesiculovirus in ZF4 cells was associated with the RLRs pathway activation by viral replicative intermediates . International Journal of Molecular Sciences, 2015;16(3):6235-50. SCI IF : 2.3
  9. Xiaodan Liu, Yi Wen, Xianqin Hu, Wenwen Wang, Xufang Liang, Jun Li, Vikram Vakharia, Li Lin* . Breaking the host range: Mandarin fish was susceptible to a vesiculovirus derived from snakehead fish. Journal of General Virology, 2015;96(Pt 4):775-81. SCI IF:3.5.
  10. Xiaoheng Zhao, Lichun Liu, Abeer M. Hegazy, Hong Wang, Jie Li, FeifeiZheng, Yang Zhou, Weimin Wang, Jun Li, Xiaoling Liu*, Li Lin*. Mannose receptor mediated phagocytosis of bacteria in macrophages of blunt snout bream (Megalobrama amblycephala) in a Ca2+-dependent manner. Fish and Shellfish Immunology, 2015; 43(2):357-363, SCI IF:3.0. JCR 一区)
  11. Weidong Zhou, Yulei Zhang, Yi Wen, Wei Ji, Yang Zhou, Yachan Ji, Xiaoling Liu, Weimin Wang, Muhammad Asim, Xufang Liang*,Taoshan Ai*, Li Lin*. Analysis of the transcriptomic profilings ofMandarin fish (Siniperca chuatsi)infected with Flavobacterium columnare with an emphasis on immune responses. Fish Shellfish Immunol. 2015; 43(1): 111-119, SCI IF:3.0. JCR 一区)
  12. Tran NT, Gao ZX, Zhao HH, Yi SK, Chen BX, Zhao YH, Lin L, Liu XQ, Wang WM*. Transcriptome analysis and microsatellite discovery in the blunt snout bream (Megalobrama amblycephala) after challenge with Aeromonas hydrophila. Fish and Shellfish Immunology, 2015, 45:72-82. SCI IF:3.0 JCR 一区)
  13. Guangxin Liu, Li Lin, Min Wang, Xueqin Liu*. Development and evaluation of a loop-mediated isothermal amplification assay for the detection of channel catfish virus. Journal of Fish Diseases, 2015, Accepted. SCI IF: 1.7. (JCR二区)
  14. Liu L, Zhu B, Wu S, Lin L, Liu G, Zhou Y, Wang W, Asim M, Yuan J, Li L, Wang M, Lu Y, Wang H, Cao J, Liu X*. Spring Viremia of Carp Virus Induces Autophagy for Necessary Viral Replication. Cell Microbiol. 2015, 17:595-605. SCI IF:4.8.
  15. Wu S, Liu L, Zohaib A, Lin L, Yuan J, Wang M, Liu X*. MicroRNA profile analysis of Epithelioma papulosum cyprini cell line before and after SVCV infection. Dev Comp Immunol. 2015, 48(1):124-8. SCI IF:3.7. JCR 二区)
  16. Li Lin*, Weimin Wang*. Lung-Kidney Dual Functions of Fish Gill. Annals of Aquaculture and Research. 2014,1(1):1003.
  17. Yuan J, Yang Y, Nie H, Li L, Gu W, Lin L, Zou M, Liu X, Wang M, Gu Z*. Transcriptome analysis of epithelioma papulosum cyprini cells after SVCV infection. BMC Genomics. 2014, 15:935. SCI IF:4.0
  18. Liu L, Zhou Y, Zhao X, Wang H, Wang L, Yuan G, Asim M, Wang W, Zeng L, Liu X*, Lin L*. Oligochitosan stimulated phagocytic activity of macrophages from blunt snout bream (Megalobrama amblycephala) associated with respiratory burst coupled with nitric oxide production. Dev Comp Immunol. 47(1):17-24, 2014. SCI IF:3.7. JCR 二区)
  19. Wang L, Liu L, Zhou Y, Zhao X, Xi M, Wei S, Fang R, Ji W, Chen N, Gu Z, Liu X, Wang W, Asim M, Liu X*, Lin L*, Molecular cloning and expression analysis of mannose receptor C type 1 in grass carp (Ctenopharyngodonidella), Dev Comp Immunol, 2014; 43(1):54-8.SCI IF:3.7. JCR 二区)
  20. Xiaoling Liu, Xiaocheng Tang, Li Wang, Jie Li, Hong Wang, Shun Wei, Rui Fang, Wei Ji, Gailing Yuan, Nan Chen, Zema Gu, Xueqin Liu, Weimin Wang, Muhammad Asim, Yang Zhou*, Li Lin*.Molecular cloning and expression analysis of mannose receptor in blunt snout bream (Megalobrama amblycephala). Molecular Biology Reports. 2014; 41(7):4601-11. SCI IF:2.5.
  21. Li Q, Liu L, Lin L, Li Z, Liu G, Wu S, Wang M, Li L, Yuan J, Yuan G, Liu X*. Immunization with recombinant baculovirus expressing the VP6 protein of grass carp reovirus induces immunity in grass carp. Virol Sin. 2014, 29(4):261-3
  22. Yang Y, Huang J, Li L, Lin L, Zhai Y, Chen X, Liu X, Wu Z, Yuan J*. Up-regulation of nuclear factor E2 - Related factor 2 upon SVCV infection. Fish Shellfish Immunol. 17;40(1):245-252, 2014. SCI IF:3.0 JCR 一区)
  23. Luo YZ, Lin L, Liu Y, Wu ZX, Gu ZM1, Li LJ*,Yuan JF*. Haematopoietic Necrosis of Cultured Silver Prussian Carp (Carassius gibelio) Associated with Cyprinid Herpesvirus. Journal of Fish Diseases,36(12):1035-1039, 2013. SCI IF:2.0. JCR 二区)
  24. Liyue Liu, Qin Li, Li Lin, Min Wang, Yuanan Lu, Weimin Wang, Junfa Yuan, Lijuan Li, Xueqin Liu*.Proteomic analysis of epithelioma papulosum cyprini cells infected with spring viraemia of carp virus. Fish and Shellfish Immunology, 35(1):26-35, 2013.SCI IF:3.0 JCR一区)
  25. Hyun-Mi Pyo, Alex Masic, Nizihti Woldeab, Carissa Embury-Hyatt, Li Lin, Yeun-Kyung Shin, Jae-Young Song, Shawn Babiuk and Yan Zhou*. Pandemic H1N1 influenza virus like particles are immunogenic and provide protective immunity to pigs. Vaccine, 30: 1297-1304, 2012.SCI IF:3.5. (JCR二区)
  26. Li Lin, Qiang Liu, Nathalie Berube, Yan Zhou*. 5’-triphosphate-siRNA: potent inhibition of influenza A virus infection by gene silencing and RIG-I activation. Journal of Virology, 86: 10359-10369, 2012.SCI IF:5.4. JCR 二区)
  27. Li Lin, Yang Li, Hyun-Mi Pyo, Xinya Lu, Sathya Narayanan, Qiang Liu and Yan Zhou*.Identification of RNA helicase A as a cellular factor that interacts with influenza A NS1 protein and its role in virus life cycle. Journal of Virology, 861942-1954, 2012.SCI IF :5.4. JCR 二区)
  28. Rajeev Boregowda, Li Lin, Laurie Ludgate1, Qin Zhu, Fang Tian, and Jianming Hu*. Cryptic protein priming sites in two different domains of duck hepatitis B virus reverse transcriptase for initiating DNA synthesis in vitro. Journal of Virology, 85: 7754-7765,2011. SCI IF:5.4. JCR 二区)
  29. Junhua Pan*, Li Lin*, Yizhi Jane Tao. Self-guanylylation of birnavirus VP1 does not require an intact polymerase activity site. Virology, 2009, 395(1):87-96. (* contributed equally). SCI IF:3.2. (JCR二区)
  30. Pan J, Dong L, Lin L, Ochoa WF, Sinkovits RS, Havens WM, Nibert ML, Baker TS, Ghabrial SA, Tao YJ , Atomic structure reveals the unique capsid organization of a dsRNA virus. Proc Natl Acad Sci U S A. 2009,106(11):4225-30. SCI IF: 9.43. JCR 一区)
  31. Jianming Hu and Li Lin. RNA-protein interactions in hepadnavirus reverse transcription. Front Biosci. 2009, 1; 14:1606-18. SCI IF: 3.7.
  32. Li Lin, F. Wan, and J Hu , Functional and Structural dynamics of Hepadnavirus Reverse Transcriptase During Protein-Primed Initiation of Reverse Transcription: Effects of metal Ions. Journal of Virology, 2008, 82:5703-5714. SCI IF: 5.4. JCR 二区)
  33. Li Lin and Hu, J. Inhibition of Hepadnavirus Reverse Transcriptase-ε RNA Interaction by Porphyrin Compounds. Journal of virology, 2008, 82: 2305-2312. SCI IF:5.4. JCR 二区)
  34. Huang J. N.*, Lin L.*, S. P. Weng and J. G. He. High expression of capsid protein of red-spotted grouper nervous necrosis virus in an avian cell line requires viral RNA2 non-coding regions. Journal of Fish Diseases, 2007, 30: 439-444 (*contributed equally). SCI IF:1.7. JCR 二区)
  35. Matthes E, A. Funk, I. Krahn, K. Gaertner, M. von Janta-Lipinski, L. Lin, H. Will, H. Sirma. Strong and Selective Inhibitors of HBV-Replication Between Novel N4-Hydroxy-and 5-Methyl-beta-L-deoxycytidine Analogues. Antimicrob Agents Chemother. 2007, 51:2523-2530. SCI IF:4.8. JCR 二区)
  36. Li Lin , Alex Prassolov, Annke Funk, Hans Will, Hueseyin Sirma et al. Evidence from nature: interspecies spread of avian hepatitis B viruses. Journal of General Virology2005 86:1335-42. SCI IF:3.4.
  37. Anneka Funk, Li Lin, Mouna Mhamdi, Hans Will, Hueseyin Sirma . Determinants of Hepadnaviral Species and Liver Cell Tropism. Monogr Virol. basel, Karger, 2005, 25: 56-65.
  38. Sirma, H., A. Funk, H. Hohenberg, M. Petrimpol, M. Mhamdi, L. Lin, U. Schubert, H. Will. Functional modulation of virus-cell interactions by drugs: new concepts for treatment of viral hepatitis and hepatocellular carcinoma. In: Proc. 11th International Symposium on Viral Hepatitis and Liver Disease. Sydney, Australia (eds: A.R. Jilbert et al.), Australian Centre for Hepatitis Virology Publisher, ISBN 1877040266, 2004: 293-296.
  39. Anneke Funk, Mouna Mhamdi, Li Lin, Hans Will, Hueseyin Sirma. Itinerary of Hepatitis B Viruses:Delineation of Restriction Points. Journal of virology, 2004, 78:8289-8300. SCI IF:5.4. JCR 二区)
  40. Li Lin , He J G, Mori K, et al. Mass mortalities associated with viral nervous necrosis in hatchery-reared groupers in the People’s Republic of China. Fish Pathology, 2001, 36: 186-188. SCI IF:1.07.
  41. 陈文捷,刘晓丹, 胡先勤,王文文, 秦真东,王瑶,周洋, 刘小玲, 林蠡*. 鱼类神经坏死病毒研究进展与发展趋势. 水产学报,2014,38:1666-1670.
  42. 刘晓丹,胡先勤,黄剑南,翁少萍,王文文,陈文捷,秦真东,董星星,周洋,刘小玲, 张学振,郭志勋,何建国*林蠡*. 原位杂交和免疫荧光检测鱼类神经坏死病毒在宿主鱼组织中的分布.水生生物学报, 2014,38 (5): 876-882.
  43. 黄剑南, 郭志勋, 冯娟, 林蠡*. 鱼类诺达病毒及其所导致的疾病. 水产学报, 2006, 30(6): 831-836.
  44. 林蠡,黄剑南, 翁少萍, 王云新,刘付永忠, 张海发,何建国. 赤点石斑鱼病毒性神经坏死症的组织病理和电镜观察. 水产学报, 2005, 29(4):519-523.
  45.  

    Beta-L-nucleosides and their use as pharmaceutical agents and their use for therapy of viral diseases. US 2006/0217345 A1, World patent, WO2005/026186 A1.美国和德国专利
  46.  

     

    Husbandry and Health Management of Grouper. Asia-Pacific Economic Cooperation Fisheries Working Group 01, 2000:1-94.(石斑鱼的培育和健康养殖,亚太经贸组织渔业工作组01,2000:1-94.)
  47.  

     

     

    《中国海洋鱼类单殖吸虫》,张剑英等,中国农业出版社,2001:1-400。


备注 获广东省科技一等奖;德国学术交流中心(DAAD)奖学金获得者;获国家自然科学基金面上项目、湖北省科技支撑计划项目、高校业务专项基金等资助。为《水产学报》编委,International Journal of Molecular Sciences(5年平均SCI=2.7)客座编委。多种国际期刊审稿人,包括Fish and Shellfish Immunology, Aquaculture等刊物。 欢迎对水生动物病害与免疫感兴趣的学生加盟。

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