储卫华,男,博士,中国药科大学生命科学与技术学院微生物教研室副教授,生物学专业硕士生导师。中国微生物学会永久会员,江苏省生物化学学会会员。南京农业大学国家重点学科动物医学博士毕业;曾在南京理工大学化工学院生物工程系、美国德州州立大学生物学系从事博士后研究。主要从事微生物与免疫学、生物制药方面的教学与科研工作。先后参与或主持国家863计划、江苏省三项工程、江苏省自然科学基金、国家质检总局等课题10余项,作为发明人申请国家发明专利7项;发表论文40余篇,其中SCI收录18篇。
研究方向与兴趣:
1、肠道微生物与微生态制剂
2、细菌耐药性及耐药性抑制剂研究
3、细菌群体感应及作为药物靶标的研究
代表性论文(SCI):
1、Weihua Chu, Shuxin Zhou, Wei Zhu & Xiyi Zhuang Quorum quenching bacteria Bacillus sp. QSI-1 protect zebrafish (Danio rerio) from Aeromonas hydrophila infection. Scientific Reports, 2014,4 : 5446 DOI: 10.1038/srep05446(SCI, 5.078)
2、Weihua Chu, Shuxin Zhou, Yan Jiang, Wei Zhu and Xiyi Zhuang. Effect of Traditional Chinese Herbal Medicine with Antiquorum Sensing Activity on Pseudomonas aeruginosa," Evidence-based Complementary and Alternative Medicine, vol. 2013, Article ID 648257, 7 pages, 2013. doi:10.1155/2013/648257 (SCI,2.175)
3、Weihua Chu, Tesfalem R. Zere, Mary M. Weber, Thomas K. Wood, Marvin Whiteley, Benjamin Hidalgo-Romano, Ernesto Valenzuela Jr, and Robert J.C. McLean*, Indole production promotes Escherichia coli mixed culture growth with Pseudomonas aeruginosa by inhibiting quorum signaling, Applied and Environmental Microbiology, 2012,Vol. 78, No. 2. 78: 411-419(SCI, 3.829).
4、Weihua Chu*, Fei Lu, Wei Zhu, Kang Chuntao. Isolation and characterization of new potential probiotic bacteria based on quorum-sensing system. Journal of Applied Microbiology, 2011,110, 202–208, DOI: 10.1111/j.1365-2672.2010.04872 x(SCI,2.386).
5、Weihua Chu, Vattem DA, Maitin V, Barnes MB, McLean RJ. Bioassays of quorum sensing compounds using Agrobacterium tumefaciens, and Chromobacterium violaceum, Methods Mol Biol. 2011; 692: 3-19(SCI).
6、Faping Tu, Weihua Chu*, Xiyi Zhuang, Chengping Lu. Effect of oral immunization with Aeromonas hydrophila ghosts on protection against experimental fish infection. Letters in Applied Microbiology. 2010,50(1): 13-17. Online: Sep 23 2009, DOI: 10.1111/j.1472-765X.2009.02746.x. (SCI 1.647)
7、Chu Wei-hua*, Zhu Wei. Isolation of Bdellovibrio as biological therapeutic agents used for the treatment of Aeromonas hydrophila infection in fish. Zoonoses and Public Health, 2010,57(4): 258-264, Online: Mar 26 2009 12:37PM, DOI: 10.1111/j. 1863-2378.2008.01224.x (SCI 2.22)
8、Chu Weihua, Lu Chengping. In vivo fish models for visualizing Aeromonas hydrophila invasion pathway using GFP as a biomarker. Aquaculture. 2008,277(3-4): 152-155 (SCI 2.044)
9、Chu Weihua. Optimization of extracellular alkaline protease production from species of Bacillus. Journal of industrial microbiology & biotechnology. 2007,34(3):241-245 (SCI)
10、Chu Weihua. Adjuvant effect of propolis on immunization by inactivated Aeromonas hydrophila in Carp (Carassius auratus gibelio),Fish and Shellfish Immunology,2006,21(1):113-117 (SCI)
联系方式:中国药科大学生命科学与技术学院微生物教研室,电话:13921443282,E-mail:chuweihua@cpu.edu.cn